I'll start with the non-Triber who happened to play for the "other" Ohio team: Chuck Tompkins. Tompkins (shown below in the only image I could find of him) was born in 1889 and played for the Reds in 1912. He pitched in one game. He pitched three innings. He gave up 5 hits and 1 run, yet netted a 0.00 ERA. I don't know enough to understand how that happens. In any case, he lived to be 86 years old and happens to be buried in the same local cemetery as my Dad.
The second person to come out of Prescott and find his way to the Bigs was Jim Moore (shown below in White Sox garb). He was born in Prescott in 1903 and played for the Indians from 1928-1929 then played for the White Sox from 1930-1932. He played in three games with the Tribe. In his debut, he pitched a complete game giving up 2 runs on 5 hits and 2 errors with 5 batters walked. He netted an ERA of 2.00. The next season, he pitched in 2 games for 5.2 innings in which he gave up 6 runs on 6 hits, 6 errors, a homer, and 4 walks. Ouch. That bit of pitching garnered a 9.53 ERA - the worst of his career. He died in Seattle and is buried in Colorado.
I was excited to find this small town bred TWO major league players! I was ECSTATIC to discover one of them was a Triber!